Comparison of vitreous/retinal pigment epithelium relative intensity in proliferative vitreoretinopathy and uveitis

Background: Quantitative measurements of vitreous inflammation using vitreous/retinal pigment epithelium-relative intensity (VIT/RPE-Relative Intensity) have been described recently. In proliferative vitreoretinopathy (PVR), plays a central role in the pathogenesis, inducing retinal fibrosis and contraction. However, no attempts yet to be made analyze severity PVR progression. Methods: A cross-sectional study was conducted by reviewing OCT image sets obtained from patients divided into four groups: (1) vitreoretinopathy, (2) intermediate posterior uveitis, (3) panuveitis, (4) normal healthy eyes Cipto Mangunkusumo Kirana Eye Hospital between April 2021 – December 2021. images were then analyzed ImageJ software for VIT/RPE-relative intensity. Results: total 19 eyes, 12 intermediate-posterior uveitis 16 panuveitis 28 recruited this study. The VIT/RPE-Relative Intensity significantly higher (0.415±0.178) than (0.236±0.043, p=0.002) (0.30±0.07, p=0.023). Compared both groups VIT/RPE relative (p = <0.001 each group). Conclusions: may offer quantitative pathogenesis PVR. Comparison with cellular is required validate finding.